13, P = 0.05) and dialysis for renal failure (13 vs. The incidence of barotrauma, the highest multiple-organ-dysfunction score, and the number of episodes of organ failure were similar in the two groups however, the numbers of patients who required paralytic agents (23 vs. 25☒2 hours, P = 0.017) than in the control group. 10.8☑.0 ml per kilogram, respectively P50 mm Hg) was more common (52 percent vs.
The patients in the limited-ventilation and control groups were exposed to different mean (±SD) tidal volumes (7.2☐.8 vs. ResultsĪ total of 120 patients with similar clinical features underwent randomization (60 in each group). All other ventilatory variables were similar in the two groups. Within 24 hours of intubation, patients at high risk for the acute respiratory distress syndrome were randomly assigned to either pressure- and volume-limited ventilation (limited-ventilation group), with the peak inspiratory pressure maintained at 30 cm of water or less and the tidal volume at 8 ml per kilogram of body weight or less, or to conventional ventilation (control group), with the peak inspiratory pressure allowed to rise as high as 50 cm of water and the tidal volume at 10 to 15 ml per kilogram. However, the efficacy of this approach has not been established. The goal is to reduce lung injury due to overdistention. The most trusted, influential source of new medical knowledge and clinical best practices in the world.Ī strategy of mechanical ventilation that limits airway pressure and tidal volume while permitting hypercapnia has been recommended for patients with the acute respiratory distress syndrome.
#Barotrauma controls license
Information and tools for librarians about site license offerings. Valuable tools for building a rewarding career in health care. The authorized source of trusted medical research and education for the Chinese-language medical community. The most advanced way to teach, practice, and assess clinical reasoning skills.
Information, resources, and support needed to approach rotations - and life as a resident. The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. NEW! Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Ĭoncise summaries and expert physician commentary that busy clinicians need to enhance patient care.
#Barotrauma controls trial
NEW! A digital journal for innovative original research and fresh, bold ideas in clinical trial design and clinical decision-making.
0 kommentar(er)
